Overview

L-ornithine-L-aspartate is a chemical made up of the two amino acids ornithine and aspartic acid. Most amino acids are used as building blocks to make protein. But L-ornithine-L-aspartate is not used to make protein. Instead it is broken down in the body to provide ornithine and aspartic acid.

L-ornithine-L-aspartate is most commonly used for reduced brain function in people with advanced liver disease (hepatic encephalopathy). It is also used for athletic performance, cirrhosis, and other conditions, but there is no good scientific evidence to support these uses.

Classification

Is a Form of:

Chemical made of ornithine and aspartic acid

Primary Functions:

Used for reduced brain fucntion in people with advanced liver disease

Also Known As:

2,5-Diaminopentanoic Acid 2-Aminobutanedioic Acid, L-Ornithin-L-Aspartat

How Does It Work?

L-ornithine-L-aspartate increases the levels of ornithine and aspartic acid in the body. These amino acids help to reduce levels of a toxic chemical called ammonia in the blood.

Uses

• Reduced brain function in people with advanced liver disease (hepatic encephalopathy).Most research shows that L-ornithine-L-aspartate may reduce symptoms of hepatic encephalopathy in people with a liver disease called cirrhosis. But most of this research is low-quality. And not all people who get hepatic encephalopathy have cirrhosis. L-ornithine-L-aspartate might not help reduce symptoms in people with other causes of hepatic encephalopathy.

Recommended Dosing

The following doses have been studied in scientific research:

ADULTS
BY MOUTH:

• For reduced brain function in people with advanced liver disease (hepatic encephalopathy): 9-18 grams daily for up to 3 months has been used.

WITH A NEEDLE:

• For reduced brain function in people with advanced liver disease (hepatic encephalopathy): 5-40 grams daily for up to 7 days has been used.

L-Ornithine-L-Aspartate Supplements Frequently Asked Questions

What is L ornithine used for?

Ornithine is commonly used by mouth for improving athletic performance. It is also used for weight loss, wound healing, and to increase sleep quality. But there is limited scientific research to support these other uses. Don't confuse ornithine with ornithine alpha-ketoglutarate (OKG) or L-Ornithine-L-Aspartate.

What is L ornithine aspartate?

L-ornithine-L-aspartate is a chemical made up of the two amino acids ornithine and aspartic acid. Most amino acids are used as building blocks to make protein. L-ornithine-L-aspartate is most commonly used for reduced brain function in people with advanced liver disease (hepatic encephalopathy).

What is L Arginine and L ornithine for?

Ornithine, the by-product of this reaction, is a precursor for the synthesis of polyamines, molecules essential for cell proliferation and differentiation. l-Arginine is also required for the synthesis of creatine, an essential energy source for muscle contraction.

How much L ornithine should I take?

How much L-Ornithine should you take? L-Ornithine supplementation (as hydrochloride), or L-Ornithine HCL, may be added to liquid or as part of a blend at 1.5g per serving to be used 1-3 times on a daily basis.

What foods contain L ornithine?

Ornithine is a naturally occurring amino acid found in meat, fish, dairy and eggs.

Does L ornithine help you sleep?

L-ornithine helps manage fatigue by stabilizing energy levels and promoting better sleep.

What are the benefits of arginine and ornithine?

Arginine and ornithine supplementation increases growth hormone and insulin-like growth factor-1 serum levels after heavy-resistance exercise in strength-trained athletes.

Clinical Studies